Segment your growing database. Profile donors for bulk messaging and reporting.
Good examples to segment your donors include:
Once you have captured your profiles you can run a report on group of them, say everyone in Cape Town, or you can run a complicated report, such as everyone in Cape Town that is interested in golf.
You can also send out targeted messages. For example, an email to everyone in Cape Town, telling them about an event happening there.
This video from the demo site shows a possible profile for a donor. Customize your profile according to your organization.